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- Increases Insulin Like Growth Factor (IGF-1), which is known to improve memory and learning.
- Amplifies and increases GHRH production and release.
- Promotes the healing of ligaments, tendons, bones and old injuries.
- Promotes increase in mineral bone density, which helps increases bone strength and prevent osteoporosis.
- Improves quality of sleep and REM duration.
- Stimulates tightening of loose skin.
- Increases the oxidation of body fat for faster fat loss.
- Increases muscle strength.
- Promotes lean muscles gains and therefore increases your BMR.
- Reduces muscle wasting.
- Promotes rejuvenation of Growth Hormone profile, thus may help fight the signs of ageing.
- Increases general sense of well-being.
Ibutamoren (MK-677) is a selective agonist of the ghrelin receptor and growth hormone secretagogue, often miss categorized as a SARM (selective androgen receptor modulator). Many of those in the fitness industry have chosen to roll with this compound vs. using growth hormone releasing peptides (GHRP’s) or human growth hormone due to cost and to avoid injecting themselves.
Ibutamoren (MK-677) is currently being developed medically to fight growth hormone and insulin-like growth factor1 (IGF-1) deficiencies in people of all ages. The FDA (food and drug administration) currently classifies it as an investigational drug and it is sitting at the preclinical stage awaiting the next step.
Even though it is not yet approved in the medical field and not yet being prescribed, it doesn’t mean that research companies haven’t come up with the idea to produce it to sell to those looking for performance enhancing. Athletes of all abilities and even average joe’s have been trying it and have reported some really cool results.
One of the first things you will notice when using Ibutamoren (MK-677) is higher appetite. Don’t worry, this isn’t your imagination, but it is actually the compound mimicking ghrelin. Ghrelin is a pretty awesome neuropeptide in our central nervous system (CNS), which our bodies produce in our stomachs, and it is classified also as a hormone. So when you take Ibutamoren (MK-677) and increase ghrelin, your hunger will go through the roof. Users report waking up in the middle of the night starving for food!
No Fat Gains
Now before you close out your browser because you think appetite increase is a bad thing for your goals, you should think again, because Ibutamoren (MK-677) also changes the way energy is spread around the body. Fat becomes metabolized different, hence obesity is blocked from occurring, and we even see evidence that those who are on the verge of type 2 diabetes can have this issue reversed. So even if you eat more, you won’t gain fat!
No Affecting Estrogen or Cortisol
The next way it works is by adding to your own bodies insulin growth factor-1 (IGF-1) and growth hormone. So it won’t shut your hormones down at all like exogenously injected human growth hormone would. It also does not increase estrogen, cortisol or other muscle eating hormones that we don’t need.
MK-677 treatment elicited a significant GH response, followed by increases in serum IGF-I and IGFBP-3, whereas effects on cortisol secretion were transient. Changes in body composition and energy expenditure were of an anabolic nature, with a sustained increase in FFM and a transient increase in BMR.
Why Use Instead of Growth Hormone?
The main reason you are better off using Ibutamoren (MK-677) and not injecting growth hormone, is what we mentioned above, which is one will add to your hormones and the other shuts you down.
But there are a couple more reasons you should take a look at it too. The first is Ibutamoren (MK-677) does not need to be mixed, refrigerated and injected, so you just take the capsules (1 per day).
The second is the cost. Good quality Human Growth hormone costs into the thousands, while Ibutamoren (MK-677) costs a fraction of that.
Why Use MK-677 Instead of Peptides?
Once again the glaring reason you want to use Ibutamoren (MK-677) instead of peptides to raise growth hormone is due to the mixing, storage, and injecting factor. But also we have seen a troubling trend where peptide companies are selling under dosed or bunk products. In fact, those in the industry estimate that almost 100% of the peptides being sold online are straight from China, and completely bunk or under dosed at best. So stop wasting your money and just buy Ibutamoren (MK-677), which can be stored for years without worry about it going rancid.
Muscle Gains & Fat Loss
Ibutamoren (MK-677) is great for those who are bulking since it increases appetite so much, allowing you to up your macros and get bigger and stronger. It also can be used to cut down body fat since it alters how our body metabolizes food. Users say they shred up even when keeping their diets the same.
Those who weight train will love the faster recovery between workouts. They also are impressed by the lean muscle mass gains and the mild strength gains they get. Endurance athletes say they see a boost in their running times too.
Injury repair is seen with Ibutamoren (MK-677) as well. Try stacking it with N2jointrx and TS Krill Oil from N2bm and you will notice a tremendous difference in how your joints and soft tissues feel. One user said all his aches and pains from years of weight training went away from using this stack for 3 months.
Those that struggle with an appetite will get instant benefits from Ibutamoren (MK-677) within the first week or two. It also will help you sleep better and harder at night, great for insomniacs.
How To Use Ibutamoren
Ibutamoren (MK-677) should be used for at least 2-3 months at 20-50mgs per day. With the average dosage of 20mgs.
It can most certainly be used solo. The half-life is only 6 hours.
For bulking stack it with 20mgs a day of RAD-140 (Testolone).
For cutting stack it with 10mgs a day of GW-501516 (Cardarine).
It also stacks well with every other SARM (selective androgen receptor modulator).
Anabolic Steroid Stacks
It is safe to also stack it with anabolic steroids. Whether you want to bulk, cut, gain strength, or gain lean muscle mass. A cool stack you can try for bodybuilding is Ibutamoren (MK-677) 20mgs per day + 500mgs per week Primobolan + 150mgs per week of Testosterone Enanthate.
Who Shouldn’t Use Ibutamoren?
We do not recommend using Ibutamoren (MK-677) if you are under 21 years old. Also if you are a tested athlete you should not use it. Since that is considered cheating, and you will be possibly be tested for it.
Women and men are both safe to use it. Those who are overweight or underweight can use it. There are very few situations where it would not be okay.
Where To Buy Mk-677?
Be very careful where you buy this compound because there are a lot of fakes being sold out there. Ibutamoren (MK-677) can be purchased via our website MedLabsAU.
The Safety and Efficacy of Growth Hormone Secretagogues
Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats
Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure.
Investigational GH drug increased muscle mass in older adults
Oral Administration of the Growth Hormone Secretagogue MK‐677 Increases Markers of Bone Turnover in Healthy and Functionally Impaired Elderly Adults
Scheduling delegates’ interim decisions and invitation for further comment: ACCS/ACMS, November 2017