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Testolone (RAD140) is currently in development by Radius Health, which is a publicly traded pharmaceutical company. The hopes are that in another decade people would be able to use this to supplement their testosterone replacement therapy. Athletes have taken advantage of the compound over the past few years, and research companies have begun selling it to help their customers with performance enhancing.
Why we need healthy testosterone levels
When was the last time you checked your testosterone levels? Some of you never have, others may have tested it once or twice in your life. We check our tire pressure, the PH of our pool, the latest sale at the mall on a weekly basis. Yet we neglect one of the most important things that dictate our health and well being for some reason, and this applies to both men and women. Yes, both genders need healthy testosterone levels or they face problems including insomnia, problems gaining strength or mass, erectile dysfunction, poor libido, bad mood, and even depression.
Testosterone levels peak in our 20’s and then start gradually tapering off as we age. Many start experiencing major problems much earlier than usual due to environmental factors, electronics, stress, and other lifestyle factors. Also, those who may have abused anabolic steroids are more likely to have poor testosterone levels.
I have low testosterone, now what?
Let’s say you get your blood work checked and your testosterone levels are low. You can try improving on your lifestyle by changing how you eat, exercising better (over-exercising can actually hurt levels too), sleeping better, and managing stress. But even if you do things perfect sometimes it just doesn’t work. This can cause you to suffer not just in the gym but also in the bedroom.
Testosterone Replacement Therapy (TRT)
The next step is testosterone replacement therapy, which can involve creams or injecting hormones. Doing this properly will put your levels back in a normal range but it does come with side effects.
Testolone (RAD140) was developed to replace those nasty creams and injections because:
- Creams can cause rashes, spread on others, and rub off- Testolone (RAD140) does none of those.
- Injections can cause infections, abscesses, and scar tissue problems. Plus they involve keeping needles in the house. Testolone (RAD140) involves none of that.
- Exogenous hormones will speed up hair loss. Testolone (RAD140) does not.
- Increasing androgenic issues like aggression and mood changes- Testolone (RAD140) will not.
- Enlarge the prostate. Testolone (RAD140) will not.
- Aromatize into estrogen, which can cause side effects like gynecomastia, water retention, bloat, and high blood pressure. Testolone (RAD140) will not.
- Shut down your pituitary glands for life. Testolone (RAD140) is only mildly suppressive.
Testolone VS Testosterone
Sounds awesome but how does it not cause problems?
Testolone (RAD140) is selective in nature. It has an 80 to 1 anabolic to androgenic ratio and it does not aromatize into estrogen. It also does not convert to dihydrotestosterone (DHT), which prevents frying of the head hair and enlarged prostate.
Taken in sum, RAD140 has all the hallmarks of a SARM. It is potency selective, since it stimulates muscle weight increases at a lower dose than that required to stimulate prostate weight increases. Moreover, it is also efficacy selective, because it is fully anabolic on muscle but demonstrates less than complete efficacy on the prostate and seminal vesicles and, in fact, can partially antagonize the stimulation of the seminal vesicles induced by testosterone.
When you use exogenous hormones like testosterone your FSH (follicle stimulating hormone) and LH (luteinizing hormone) drops to 0 because they signal your pituitary glands to completely go dormant. This means your own body no longer produces hormones. Testolone (RAD140) meanwhile will suppress you much less, and you will be better able to recover later on if you change your mind. This makes it a much more flexible choice in case you want to have children one day or you want to come off everything.
Since Testolone (RAD140) is non-androgenic, it is perfectly safe for females to use. It won’t cause virilization issues like man-like physical features, deepening voice, enlarged clitoris, body hair or aggression. Females will run 10mgs per day.
Testolone (RAD140) is great to use for anyone, but those in fitness especially will appreciate the benefits it gives.
- Lean muscle gains
- Fat loss
- Better results in the bedroom
- Better recovery and repair
- A boost in sleep
- Rise in mood
Testolone (RAD140) is suppressive, but not even close to as much as exogenous hormones. A post cycle therapy is needed when you come off.
How to use
Testolone (RAD140) can be used solo or as part of a stack. Males typically will run 20mgs per day. Do not exceed 40mgs a day.
If you choose to cycle the compound run it 12-16 weeks and take 6-8 weeks off including post cycle.
It stacks well with any SARM (selective androgen receptor modulator). Those who want to bulk can stack it with LGD-4033 (Ligandrol). Those who want to cut can use it with GW-501516 (Cardarine). And finally, those who want improvements to recovery and injuries can stack it with MK-2866 (Ostarine).
With Anabolic Steroids
The nice thing about Testolone (RAD140) is you can use it as your ‘testosterone base’ in a steroid cycle. This helps cut down on side effects. In this scenario, you would simply substitute it at 20mgs a day for Testosterone, along with whatever steroids you choose.
The half-life is quite long, around 20 hours. So once a day dosing is fine, although some will split the dosage in half.
Where to find
Testolone (RAD140) is becoming harder to find due to the government crackdowns and also credit card processors banning the sale. This has led many research companies to go out of business. Luckily we are still selling the product and we are a legitimate source!
Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140
Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action
NCI Drug Dictionary – selective androgen receptor modulator RAD140
Selective Androgen Receptor Modulator RAD140 Is Neuroprotective in Cultured Neurons and Kainate-Lesioned Male Rats